FPGEE 無料問題集「NABP Foreign Pharmacy Graduate Equivalency Examination」

（A）Not shown to reduce sudden death or prolong survival.

（B）Pyrophosphate analog

（C）Metabolism in liver is by glucuronidization

（D）Inhibition of DNA gyrase results in:
1 . Inhibition of bacterial replication 2. Inhibition of DNA repair 3. Inhibition of expression of certain operons

（E）Non-nucleoside reverse transcriptase inhibitor

（A）Chloroquine

（B）Primaquine

（C）Hydroxycloroquine

（D）Sulfasalazine

（E）Quinine

（A）Hydroxyls 1 and 2

（B）Hydroxyl 1

（C）Hydroxyl 4

（D）Hydroxyl 2

（E）Hydroxyl 3

（A）None of the above

（B）Glucose + Fatty acids

（C）Saturated + Unsaturated acids

（D）Fatty acids + Triglycerides

（E）Glycerol + Fatty acids

（A）Cognitive side effects, respiratory depression.

（B）Effects in hypertension:
1 . Blood pressure - decrease
2 . Systemic vascular resistance -decrease
3 . Heart rate - no change
4 . Stroke volume - no change
5 . Ejection fraction - no change
6 . Venous capacitance - increase
7 . Pulmonary capillary wedge pressure - no change
8 . Renin -increase
9 . Plasma aldosterone - decrease
1 0. Plasma norepinephrine - no change

（C）Few cognitive or behavioral side effects.

（D）Is found in breast milk.

（E）Generally very effective as a single drug.

（A）Proton donor ion

（B）Anionic

（C）Proton acceptor ion

（D）Cationic

（E）Neutral ion

（A）Ester hydrolysis

（B）Glucuronide conjugation

（C）A & B

（D）All of the above

（E）N-oxidation

（A）All are correct

（B）Non-oxidative cleavage of phosphirin ring

（C）Formation of biliverdin

（D）Formation of bile pigments

（E）Formation of urobilinogen

（A）Diabetes mellitus

（B）Hearing impairment

（C）Pregnancy

（D）Diabetes

（E）Hyperlipidemia

（A）III only

（B）All are correct

（C）II and III only

（D）I and II only

（E）I only

（A）Azoles antifungal act blocking the synthesis of ergosterol.

（B）Polyene antifungal act binding to ergosterol from pores resulting in linkage of cellular.

（C）Side effects of antifungals cannot be treat for Tylenol due to high drug interaction.

（D）Polyene antifungal has the widest spectrum compared to any other agent

（E）Side effects of antifungals include fever, chills, anorexia, headaches and muscle pain

（A）75 to 135 mEq/L

（B）135 to 147mEq/L

（C）125 to 145 mEq/L

（D）147 to 150 mEq/L

（E）35 to 47 mEq/L

（A）All are drug metabolizing isoforms

（B）CYP2C9

（C）CYP3A4

（D）CYP51

（E）CYP1A2

（A）Oxacillin

（B）Nafcillin

（C）Amoxicillin

（D）Methicillin

（E）All are very narrow spectrum penicillins